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Article

The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways.

Nature - 10 May 2001

Tarricone C, Xiao B, Justin N, Walker P A, Rittinger K, Gamblin S J, Smerdon S J

Abstract excerpt

Small G proteins are GTP-dependent molecular switches that regulate numerous cellular functions. They can be classified into homologous subfamilies that are broadly associated with specific biological processes. Cross-talk between small G-protein families has an important role in signalling, but the mechanism by which it occurs is poorly understood. The coordinated action of Arf and Rho family GTPases is required...

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Identifiers

PMID: 11346801
DOI: 10.1038/35075620

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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