Article
Mypt1-mediated spatial positioning of Bmp2-producing cells is essential for liver organogenesis.
Development (Cambridge, England) - 1 Oct 2008
Huang Honghui, Ruan Hua, Aw Meng Yuan, Hussain Alamgir, Guo Lin, Gao Chuan, Qian Feng, Leung Thomas, Song Haiwei, Kimelman David, Wen Zilong, Peng Jinrong
Abstract excerpt
Mesodermal tissues produce various inductive signals essential for morphogenesis of endodermal organs. However, little is known about how the spatial relationship between the mesodermal signal-producing cells and their target endodermal organs is established during morphogenesis. Here, we report that a mutation in the zebrafish myosin phosphatase targeting subunit 1 (mypt1) gene causes abnormal bundling of actin...
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