Article
Development of spontaneous anergy in invariant natural killer T cells in a mouse model of dyslipidemia.
Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2010
Braun Nicole A, Mendez-Fernandez Yanice V, Covarrubias Roman, Porcelli Steven A, Savage Paul B, Yagita Hideo, Van Kaer Luc, Major Amy S
Abstract excerpt
OBJECTIVE: In this study, we investigated whether dyslipidemia-associated perturbed invariant natural killer T (iNKT) cell function is due to intrinsic changes in iNKT cells or defects in the ability of antigen-presenting cells to activate iNKT cells. METHODS AND RESULTS: We compared iNKT cell ex...
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