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Article

Shift-invariant adaptive double threading: learning MHC II-peptide binding.

Journal of computational biology : a journal of computational molecular cell biology - 1 Sept 2008

Zaitlen Noah, Reyes-Gomez Manuel, Heckerman David, Jojic Nebojsa

Abstract excerpt

The major histocompatibility complex (MHC) plays important roles in the workings of the human immune system. Specificity of MHC binding to peptide fragments from cellular and pathogens' proteins has been found to correlate with disease outcome and pathogen or cancer evolution. In this paper we propose a novel approach to predicting binding configurations and energies for MHC class II molecules, whose epitopes are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18771399
DOI: 10.1089/cmb.2007.0183

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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