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Article

Learning MHC I—peptide binding

15 Jul 2006

Abstract excerpt

MOTIVATION AND RESULTS: Motivated by the ability of a simple threading approach to predict MHC I--peptide binding, we developed a new and improved structure-based model for which parameters can be estimated from additional sources of data about MHC-peptide binding. In addition to the known 3D structures of a small number of MHC-peptide complexes that were used in the original threading approach, we included three...

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PMID: 16873476
DOI: 10.1093/bioinformatics/btl255

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