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Article

p53 codon 72 polymorphism and HPV status in lung cancer.

Medical science monitor : international medical journal of experimental and clinical research - 1 Sept 2008

Buyru Nur, Altinisik Julide, Isin Mustafa, Dalay Nejat

Abstract excerpt

BACKGROUND: Several risk factors, both environmental and genetic, have been associated with the pathogenesis of lung cancer. A common polymorphism at codon 72 of exon 4 of the p53 gene encoding either an arginine or proline has been shown to confer susceptibility to the development of different human malignancies. This polymorphism affects proteolytic degradation of p53 promoted by the HPV-E6 protein and...

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PMID: 18758421

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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