Article
An increased lung cancer risk associated with codon 72 polymorphism in the TP53 gene and human papillomavirus infection in Mazandaran province, Iran.
Lung cancer (Amsterdam, Netherlands) - 1 May 2007
Nadji Seyed Alireza, Mahmoodi Mahmood, Ziaee Abed Ali, Naghshvar Farshad, Torabizadeh Jila, Yahyapour Yousef, Nategh Rakhshandeh, Mokhtari-Azad Talat
Abstract excerpt
The TP53 gene has a polymorphism in exon 4 at codon 72 that presents the arginine or proline genotype. The association of TP53 codon 72 polymorphism with lung cancer risk has been studied by several groups, although with inconsistent results. Our previous study showed that the human papillomavirus (HPV) infection is associated with the development of lung cancer in Mazandaran, north part of Iran (cases=25.6%...
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