Polymorphism of the p53 gene within the codon 72 in lung cancer patients.

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Article

Polymorphism of the p53 gene within the codon 72 in lung cancer patients.

Neoplasma - 1 Jan 2001

Biros E, Kalina I, Biros I, Kohut A, Bogyiová E, Salagovic J, Stubna J

Abstract excerpt

We tested the codon 72 single nucleotide polymorphism (SNP) of the tumor suppressor gene p53 for association with lung cancer. In our hospital-based case-control study, 168 lung cancer patients (134 males and 34 females) and 148 controls without malignant diseases were recruited. The genotype characteristics were determined by PCR-based RFLP method using DNA extracted from peripheral blood. Only in lung cancer...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Case-Control Studies
Electrophoresis, Polyacrylamide Gel
Female
Genes, p53
Genotype
Homozygote
Humans
Lung Neoplasms
Male
Middle Aged
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Time Factors

Source

Open in PubMed

Identifiers

PMID: 11845987

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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