Article
Endothelial protein C receptor polymorphisms and risk of myocardial infarction.
Haematologica - 1 Sept 2008
Medina Pilar, Navarro Silvia, Corral Javier, Zorio Esther, Roldán Vanessa, Estellés Amparo, Santamaría Amparo, Marín Francisco, Rueda Joaquín, Bertina Rogier M, España Francisco
Abstract excerpt
BACKGROUND: Haplotypes A1 and A3 in the endothelial protein C receptor gene are tagged by the 4678G/C and 4600A/G polymorphisms, respectively, and have been reported to influence the risk of venous thromboembolism. We assessed whether these haplotypes modify the risk of premature myocardial infarction. DESIGN AND METHODS: We genotyped these polymorphisms in 689 patients with premature myocardial infarction and...
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