Article
Haplotypes of the endothelial protein C receptor gene and Behçet's disease.
Thrombosis research - 1 Apr 2012
Navarro Silvia, Bonet Elena, Medina Pilar, Martos Laura, Ricart José M, Vayá Amparo, Todolí José, Fontcuberta Jordi, Estellés Amparo, España Francisco
Abstract excerpt
INTRODUCTION: Behçet's disease is a vasculitis of unknown cause in which thrombosis occurs in about 25% of patients. Two haplotypes of the endothelial protein C receptor gene, H1 and H3, are associated with the risk of thrombosis. Thus, the objective of this study was to evaluate the influence of these haplotypes on the thrombosis risk in Behçet's disease. MATERIAL AND METHODS: We evaluated the H1 and H3...
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