Article
Genotypes and haplotypes predisposing to myocardial infarction: a multilocus case-control study.
European heart journal - 1 Mar 2004
Tobin Martin D, Braund Peter S, Burton Paul R, Thompson John R, Steeds Richard, Channer Kevin, Cheng Suzanne, Lindpaintner Klaus, Samani Nilesh J
Abstract excerpt
AIM: To identify polymorphisms and haplotypes in candidate genes that predispose to myocardial infarction (MI) using a multilocus approach. METHODS AND RESULTS: 1052 subjects, comprising 547 acute MI cases and 505 controls were studied. The association between MI and 58 SNPs in 35 candidate genes (generating 61 016 individual genotypes), and between MI and estimated haplotypes at 14 loci encompassing 16 genes was...
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