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Article

Functional analysis of two haplotypes of the human endothelial protein C receptor gene.

Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2014

Medina P, Navarro S, Bonet E, Martos L, Estellés A, Bertina R M, Vos H L, España F

Abstract excerpt

OBJECTIVE: To confirm the effect of the endothelial protein receptor gene (PROCR) haplotypes H1 and H3 on venous thromboembolism (VTE), to study their effect on endothelial protein C receptor (EPCR) expression in human umbilical vein endothelial cells, and to investigate the functionality of H1 tagging single-nucleotide polymorphisms in an in vitro model. APPROACH AND RESULTS: Protein C (PC), activated PC, and...

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Identifiers

PMID: 24436369
DOI: 10.1161/ATVBAHA.113.302518

Genes

PROCR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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