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Article

Expression and mutation analysis of epidermal growth factor receptor in head and neck squamous cell carcinoma.

Cancer science - 1 Aug 2008

Sheikh Ali Mahmoud A L, Gunduz Mehmet, Nagatsuka Hitoshi, Gunduz Esra, Cengiz Beyhan, Fukushima Kunihiro, Beder Levent Bekir, Demircan Kadir, Fujii Masae, Yamanaka Noboru, Shimizu Kenji, Grenman Reidar, Nagai Noriyuki

Abstract excerpt

The epidermal growth factor receptor (EGFR)-RAS-RAF-mitogen-activated protein kinase signaling cascade is an important pathway in cancer development and recent reports show that EGFR and its downstream signaling molecules are mutated in a number of cancers. We have analyzed 91 Japanese head and neck squamous cell carcinomas (HNSCC) and 12 HNSCC cell lines for mutations in EGFR, ErbB2, and K-ras. Exons encoding...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Neoplasms, Squamous Cell

Source

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Identifiers

PMID: 18754871
DOI: 10.1111/j.1349-7006.2008.00861.x
PMCID: PMC11158168

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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