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Article

Functional mutation analysis of EGFR family genes and corresponding lymph node metastases in head and neck squamous cell carcinoma.

Clinical & experimental metastasis - 1 Jan 2012

Hama Takanori, Yuza Yuki, Suda Toshihito, Saito Yoshimichi, Norizoe Chihiro, Kato Takakuni, Moriyama Hiroshi, Urashima Mitsuyoshi

Abstract excerpt

Tumors with certain mutations in the epidermal growth factor receptor (EGFR) family genes dramatically respond to EGFR inhibitors. Therefore, these mutations are important factors that influence disease progression and patient survival. We previously studied the mutation status of EGFR in patients with head and neck squamous cell carcinoma (HNSCC). However, the mutation status of lymph node metastases and the...

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PMID: 21953075
DOI: 10.1007/s10585-011-9425-5

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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