Article
Prognostic significance of epidermal growth factor receptor phosphorylation and mutation in head and neck squamous cell carcinoma.
The oncologist - 1 Sept 2009
Hama Takanori, Yuza Yuki, Saito Yoshimichi, O-uchi Jin, Kondo Shu, Okabe Masataka, Yamada Hisashi, Kato Takakuni, Moriyama Hiroshi, Kurihara Satoshi, Urashima Mitsuyoshi
Abstract excerpt
The molecular status of the epidermal growth factor receptor (EGFR) has not been as well studied in head and neck squamous cell carcinoma (HNSCC) as in lung cancer. We examined the frequencies of EGFR mutations as well as the expression/phosphorylation status of the EGFR protein in HNSCC patients. Moreover, we tried to elucidate associations between EGFR molecular status and patient characteristics and...
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