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Article

Detection of EGFR- and HER2-activating mutations in squamous cell carcinoma involving the head and neck.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 May 2006

Willmore-Payne Carlynn, Holden Joseph A, Layfield Lester J

Abstract excerpt

Recent reports have indicated that mutations in the epidermal growth factor receptor-1 (EGFR) occur in about 7% of patients with squamous cell carcinoma of the head and neck. It is known that many patients with non-small-cell lung cancer who respond to the EGFR inhibitors gefitinib and erlotinib have tumors with EGFR-activating mutations. This might suggest that patients with head and neck squamous carcinoma, who...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to ErbB Receptors

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Source

Identifiers

PMID: 16547470
DOI: 10.1038/modpathol.3800552

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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