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EGFR and erbB2 mutation status in Japanese lung cancer patients

7 Jul 2005

Abstract excerpt

Much evidence has accumulated that the epidermal growth factor receptor (EGFR) and its family members are strongly implicated in the development and progression of lung cancers. Somatic mutations of the EGFR gene were found in about 25-40% of Japanese lung cancer patients. More recently, erbB2 mutations are found in about 4% of European-derived lung cancer patients. We have investigated EGFR and erbB2 mutation...

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PMID: 16003726
DOI: 10.1002/ijc.21301

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