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Article

Autophagy competes for a common phosphatidylethanolamine pool with major cellular PE-consuming pathways in Saccharomyces cerevisiae.

Genetics - 1 Feb 2015

Wilson-Zbinden Caroline, dos Santos Aline Xavier da Silveira, Stoffel-Studer Ingrid, van der Vaart Aniek, Hofmann Kay, Reggiori Fulvio, Riezman Howard, Kraft Claudine, Peter Matthias

Abstract excerpt

Autophagy is a highly regulated pathway that selectively degrades cellular constituents such as protein aggregates and excessive or damaged organelles. This transport route is characterized by engulfment of the targeted cargo by autophagosomes. The formation of these double-membrane vesicles requires the covalent conjugation of the ubiquitin-like protein Atg8 to phosphatidylethanolamine (PE). However, the origin...

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Identifiers

PMID: 25519895
DOI: 10.1534/genetics.114.169797
PMCID: PMC4317655

Genes

ATG7
GPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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