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Article

A 3'-untranslated region polymorphism in the TBX21 gene encoding T-bet is a risk factor for genital herpes simplex virus type 2 infection in humans.

The Journal of general virology - 1 Sept 2008

Svensson Alexandra, Bergin Ann-Marie H, Löwhagen Gun-Britt, Tunbäck Petra, Bellner Lars, Padyukov Leonid, Eriksson Kristina

Abstract excerpt

It was recently shown that the transcription factor T-bet is crucial for adequate innate and acquired immune responses to genital herpes simplex virus type 2 (HSV-2) infection in mice. To test the possible genetic influence of variations in the TBX21 gene encoding T-bet on susceptibility to infection, this study evaluated the frequencies of five different single-nucleotide polymorphisms (SNPs) in the human TBX21...

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Source

Identifiers

PMID: 18753235
DOI: 10.1099/vir.0.2008/001305-0

Genes

TBX21

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A 3'-untranslated region polymorphism in the TBX21 gene encoding T-bet is a risk factor for genital herpes simplex virus type 2 infection in humans.PMID 18753235Read ↗

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