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Correlation of TBX21 gene polymorphisms with ankylosing spondylitis in a Chinese population.

International journal of immunogenetics - 1 Jun 2024

Li Lin, Shan Jiankang, Fang Haixin, An Guangqi, Zhang Min, Zhou Pengyi, Xie Kunpeng, Jin Bo, Zhu Haiyan, Jin Xuemin, Yang Peizeng, Du Liping

Abstract excerpt

Genome-wide association studies analysis has revealed associations between ankylosing spondylitis (AS) and loci on the TBX21 gene across various populations. This study aimed to investigate if there is a connection between a higher risk of AS in a Chinese population and two polymorphism loci on the TBX21 gene. To achieve this, we performed a case-control investigation involving 363 patients with AS and 907...

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China
East Asian People
Genome-Wide Association Study
Haplotypes
HLA-B27 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Spondylitis, Ankylosing

T-bet Transcription Factor

T-Box Domain Proteins

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Identifiers

PMID: 38468428
DOI: 10.1111/iji.12659

Genes

TBX21

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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