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Article

Association of TBX21 polymorphisms in a Korean population with rheumatoid arthritis.

Experimental & molecular medicine - 31 Jan 2009

Chae Soo Cheon, Shim Seung Cheol, Chung Hun Taeg

Abstract excerpt

TBX21 (T-bet) is a member of the T-box family of transcriptional factors that contain a conserved DNA binding domain. TBX21 is a critical regulator of the commitment to the Th1 lineage and IFN-gamma production. Th1 and Th2 cells cross-regulate the differentiation of each other, and in this way TBX21 could be an attractive candidate gene for treating autoimmune disease such as rheumatoid arthritis (RA). In present...

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Identifiers

PMID: 19287198
DOI: 10.3858/emm.2009.41.1.005
PMCID: PMC2679282

Genes

TBX21

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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