CYP1A2 164 A-->C polymorphism, cigarette smoking, consumption of well-done red meat and risk of developing colorectal adenomas and carcinomas.

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Article

CYP1A2 164 A-->C polymorphism, cigarette smoking, consumption of well-done red meat and risk of developing colorectal adenomas and carcinomas.

Anticancer research - 1 Jan 2000

Saebø Mona, Skjelbred Camilla F, Brekke Li Karin, Bowitz Lothe Inger Marie, Hagen Per Chr, Johnsen Egil, Tveit Kjell M, Kure Elin H

Abstract excerpt

BACKGROUND: Genetic polymorphisms in metabolizing enzymes may modify the association of environmental exposure on colorectal cancer (CRC) and adenoma risk. MATERIALS AND METHODS: One hundred and ninety-eight CRC cases, 422 adenomas (206 low-risk and 216 high-risk adenomas) and 222 controls were genotyped for the CYP1A2 164 A-->C polymorphism and questionnaires were used to assess environmental exposure. RESULTS:...

Topics

Adenoma
Aged
Case-Control Studies
Colorectal Neoplasms
Cytochrome P-450 CYP1A2
Diet
Female
Genotype
Humans
Male
Meat
Middle Aged
Polymorphism, Single Nucleotide
Smoking

Source

Open in PubMed

Identifiers

PMID: 18751408

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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