Article
The CYP1A1 genotype may alter the association of meat consumption patterns and preparation with the risk of colorectal cancer in men and women.
The Journal of nutrition - 1 Feb 2005
Murtaugh Maureen A, Sweeney Carol, Ma Khe-ni, Caan Bette J, Slattery Martha L
Abstract excerpt
We hypothesized that the risk of colorectal cancer associated with meat preparation methods producing heterocyclic amines or polycyclic aromatic hydrocarbons is modified by the CYP1A1 genotype alone or in combination with the GSTM1 genotype or the NAT2 imputed phenotype. A total of 952 rectal cancer cases and 1205 controls (between September 1997 and February 2002) and 1346 colon cancer cases and 1544 controls...
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