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Article

Interaction of the yeast omnipotent suppressors SUP1(SUP45) and SUP2(SUP35) with non-mendelian factors.

Genetics - 1 Jul 1991

Dagkesamanskaya A R, Ter-Avanesyan M D

Abstract excerpt

The SUP1 and SUP2 genes code for protein factors intimately involved in the control of translational accuracy. The disrupted alleles of these genes confer a recessive lethal phenotype in both [psi+] and [psi-] genetic backgrounds, indicating an essential function for the corresponding proteins. I...

Topics

Alleles
Blotting, Southern
Genes, Dominant
Genes, Lethal
Genes, Recessive
Genes, Suppressor
Guanidine
Guanidines
Mutation
Phenotype
Plasmids
Protein Biosynthesis
Saccharomyces cerevisiae

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Identifiers

PMID: 1874413
DOI: 10.1093/genetics/128.3.513
PMCID: PMC1204525

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1874413-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Interaction of the yeast omnipotent suppressors SUP1(SUP45) and SUP2(SUP35) with non-mendelian factors.PMID 1874413Read ↗

Isolation and characterization of omnipotent suppressors in the yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Novel non-Mendelian determinant involved in the control of translation accuracy in Saccharomyces cerevisiae.Semantic proximity Read ↗

The [PSI+] prion of yeast: a problem of inheritance.Semantic proximity Read ↗

The yeast non-Mendelian factor [ETA+] is a variant of [PSI+], a prion-like form of release factor eRF3.Semantic proximity Read ↗

Isolation of omnipotent suppressors in an [eta+] yeast strain.Semantic proximity Read ↗

The PNM2 mutation in the prion protein domain of SUP35 has distinct effects on different variants of the [PSI+] prion in yeast.Semantic proximity Read ↗

Epigenetic regulation of translation reveals hidden genetic variation to produce complex traits.Semantic proximity Read ↗

Propagation of the yeast prion-like [psi+] determinant is mediated by oligomerization of the SUP35-encoded polypeptide chain release factor.Semantic proximity Read ↗

Translation termination efficiency can be regulated in Saccharomyces cerevisiae by environmental stress through a prion-mediated mechanism.Semantic proximity Read ↗

C-terminal truncation of the Sup35 protein increases the frequency of de novo generation of a prion-based [PSI+] determinant in Saccharomyces cerevisiae.Semantic proximity Read ↗

Ssb1 chaperone is a [PSI+] prion-curing factor.Semantic proximity Read ↗

[Psi(+)] prion generation in yeast: characterization of the 'strain' difference.Semantic proximity Read ↗

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