Article
Panton-Valentine leukocidin is not a virulence determinant in murine models of community-associated methicillin-resistant Staphylococcus aureus disease.
The Journal of infectious diseases - 15 Oct 2008
Bubeck Wardenburg Juliane, Palazzolo-Ballance Amy M, Otto Michael, Schneewind Olaf, DeLeo Frank R
Abstract excerpt
Increases in the incidence and severity of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections have spawned efforts to define unique virulence properties among prevalent strains. Panton-Valentine leukocidin (PVL), a pore-forming cytotoxin, has garnered attention because of its epidemiologic association with CA-MRSA. Using both the clinical isolate LAC, which is representative of...
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