Article
Do differences in Panton-Valentine leukocidin production among international methicillin-resistant Staphylococcus aureus clones affect disease presentation and severity?
Journal of clinical microbiology - 1 May 2012
Boakes Eve, Kearns Angela M, Badiou Cederic, Lina Gerard, Hill Robert L, Ellington Matthew J
Abstract excerpt
Panton-Valentine leukocidin (PVL) production by methicillin-resistant Staphylococcus aureus (MRSA) was determined in vitro using the enzyme-linked immunosorbent assay (ELISA), and associations with clinical presentation and bacterial genetic characteristics were examined. PVL production ranged from 0.02 to 4.865 μg/ml and correlated with a multilocus sequence type (MLST) clonal complex associated with specific...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Bacterial Toxins
- Child
- Child, Preschool
- Enzyme-Linked Immunosorbent Assay
- Exotoxins
- Female
- Genotype
- Humans
- Infant
- Infant, Newborn