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Article

Panton-Valentine leukocidin is not the primary determinant of outcome for Staphylococcus aureus skin infections: evaluation from the CANVAS studies.

PloS one - 1 Jan 2012

Tong Amy, Tong Steven Y C, Zhang Yurong, Lamlertthon Supaporn, Sharma-Kuinkel Batu K, Rude Thomas, Ahn Sun Hee, Ruffin Felicia, Llorens Lily, Tamarana Ganesh, Biek Donald, Critchley Ian, Fowler Vance G

Abstract excerpt

The impact of Panton-Valentine leukocidin (PVL) on the severity of complicated skin and skin structure infections (cSSSI) caused by Staphylococcus aureus is controversial. We evaluated potential associations between clinical outcome and PVL presence in both methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus (MSSA) isolates from patients enrolled in two large, multinational phase three...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 22623995
DOI: 10.1371/journal.pone.0037212
PMCID: PMC3356380

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Panton-Valentine leukocidin is not the primary determinant of outcome for Staphylococcus aureus skin infections: evaluation from the CANVAS studies.PMID 22623995Read ↗

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