Article
Augmented production of Panton-Valentine leukocidin toxin in methicillin-resistant and methicillin-susceptible Staphylococcus aureus is associated with worse outcome in a murine skin infection model.
The Journal of infectious diseases - 1 Jan 2010
Varshney Avanish K, Martinez Luis R, Hamilton Stephanie M, Bryant Amy E, Levi Michael H, Gialanella Philip, Stevens Dennis L, Fries Bettina C
Abstract excerpt
The role of Panton-Valentine leukocidin (PVL) in Staphylococcus aureus infections is controversial. We used a mouse model of skin infection to compare the virulence of methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus (MSSA) strains with different levels of PVL producti...
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