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Risk of celiac disease in children with type 1 diabetes is modified by positivity for HLA-DQB102-DQA105 and TNF -308A.

Diabetes care - 1 Apr 2006

Sumnik Zdenek, Cinek Ondrej, Bratanic Nina, Kordonouri Olga, Kulich Michal, Roszai Barnabas, Arato Andras, Lebl Jan, Soltesz Gyula, Danne Thomas, Battelino Tadej, Schober Edit

Abstract excerpt

OBJECTIVE: The overlap between genetic susceptibility to celiac disease (CD) and to type 1 diabetes is incomplete; therefore, some genetic polymorphisms may significantly modify the risk of CD in subjects with type 1 diabetes. This study aimed to investigate whether the susceptibility to CD in diabetic children is modified by positivity for HLA-DQB1*02-DQA1*05 and DQB1*0302-DQA1*03 and by alleles of single...

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PMID: 16567828
DOI: 10.2337/diacare.29.04.06.dc05-1923

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TNF
CTLA4

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