Article
HLA Genotyping in Children With Celiac Disease Allows to Establish the Risk of Developing Type 1 Diabetes.
Clinical and translational gastroenterology - 1 Jul 2024
Schirru Enrico, Rossino Rossano, Diana Daniela, Jores Rita D, Baldera Davide, Muntoni Sandro, Spiga Claudia, Ripoli Carlo, Ricciardi Maria R, Cucca Francesco, Congia Mauro
Abstract excerpt
INTRODUCTION: Celiac disease (CD) and type 1 diabetes (T1D) often co-occur and share genetic components in the human leukocyte antigen (HLA) class II region. We aimed to study the usefulness of HLA genotyping in predicting the risk of developing T1D in patients with CD and the temporal relationship between these diseases. METHODS: A cohort of 1,886 Sardinian patients, including 822 with CD, 1,064 with T1D, and...
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