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Article

Evidence of epistasis between interleukin 1 and selenoprotein-S with susceptibility to rheumatoid arthritis.

Annals of the rheumatic diseases - 1 Sept 2009

Marinou I, Walters K, Dickson M C, Binks M H, Bax D E, Wilson A G

Abstract excerpt

OBJECTIVE: Selenoprotein-S (SELS) is involved in the stress response within the endoplasmic reticulum (ER) and inflammation. Recently, promoter variants in the SELS gene were shown to be associated with plasma levels of interleukin (IL)6, IL1beta and tumour necrosis factor (TNF). It was hypothesi...

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Share to Arthritis, Rheumatoid
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Share to Epistasis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Interleukin-1

Share to Membrane Proteins

Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 18728048
DOI: 10.1136/ard.2008.090001

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18728048-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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