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Article

The role of the GABRA2 polymorphism in multiplex alcohol dependence families with minimal comorbidity: within-family association and linkage analyses.

Journal of studies on alcohol and drugs - 1 Sept 2007

Matthews Abigail G, Hoffman Eric K, Zezza Nicholas, Stiffler Scott, Hill Shirley Y

Abstract excerpt

OBJECTIVE: The genes encoding the gamma-aminobutyric acid(A) (GABA(A)) receptor have been the focus of several recent studies investigating the genetic etiology of alcohol dependence. Analyses of multiplex families found a particular gene, GABRA2, to be highly associated with alcohol dependence, using within-family association tests and other methods. Results were confirmed in three case-control studies. The...

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Source

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Identifiers

PMID: 17690794
DOI: 10.15288/jsad.2007.68.625
PMCID: PMC3285563

Genes

GABRA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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