Article
Genetic variability of the high-affinity IgE receptor alpha-subunit (FcepsilonRIalpha).
Immunologic research - 1 Jan 2009
Potaczek Daniel P, Nishiyama Chiharu, Sanak Marek, Szczeklik Andrew, Okumura Ko
Abstract excerpt
Our knowledge on the variability of FCER1A gene encoding for alpha-subunit of the high-affinity immunoglobulin E receptor (FcepsilonRI) that plays a central role in the pathogenesis of allergy and related disorders, has been recently much extended. Last findings from FCER1A mutational screening and genetic association studies, followed by functional analyses of the polymorphisms, are briefly summarized in this...
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