Article
SNPs in the FCER1A gene region show no association with allergic rhinitis in a Han Chinese population.
PloS one - 31 Dec 2010
Zhang Yuan, Duan Su, Lin Xiaoping, Zhang Wei, Meng Na, Zhao Liping, Zhao Yan, Han Demin, Zhang Luo
Abstract excerpt
BACKGROUND: Immunoglobulin E (IgE) is a central player in the allergic response, and raised total IgE levels are considered as an indicator of atopy or potential development of atopy. A recent genome-wide scan in a German population-based cohort of adults identified the gene encoding the alpha chain of the high affinity receptor for IgE (FCER1A) as a susceptibility locus influencing total serum IgE levels. The...
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