Article
Sequence variants in the FcepsilonRI alpha chain gene.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 Jul 2002
Shikanai Toshiki, Silverman Eric S, Morse Brian W, Lilly Craig M, Inoue Hiroshi, Drazen Jeffrey M
Abstract excerpt
There is a relationship between IgE levels and expression of high-affinity IgE receptors (FcepsilonRI). Because the alpha chain is the only portion of the receptor that binds directly to IgE, we reasoned that sequence variants in the FcepsilonRI alpha gene may exist that alter these binding event...
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