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Article

miRNAs Alter T Helper 17 Cell Fate in the Pathogenesis of Autoimmune Diseases

21 Apr 2021

Abstract excerpt

T helper 17 (Th17) cells are characterized by the secretion of the IL-17 cytokine and are essential for the immune response against bacterial and fungal infections. Despite the beneficial roles of Th17 cells, unrestrained IL-17 production can contribute to immunopathology and inflammatory autoimmune diseases, including multiple sclerosis, rheumatoid arthritis, and inflammatory bowel disease. Although these...

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PMID: 33968012
DOI: 10.3389/fimmu.2021.593473

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