Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of MicroRNA on Regulatory T Cells and Implications for Adoptive Cellular Therapy to Ameliorate Graft-versus-Host Disease

31 Jan 2018

Abstract excerpt

Regulatory T cells (Tregs) are key mediators of the immune system. MicroRNAs (miRNAs) are a family of ~22 nucleotide non-coding RNAs that are processed from longer precursors by the RNases Drosha and Dicer. miRNA regulates protein expression posttranscriptionally through mRNA destabilization or translational silencing. A critical role for miRNA in Treg function was initially discovered when both Dicer and Drosha...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mesenchymal stem cell research
Share to MicroRNA in disease regulation
Share to RNA Interference and Gene Delivery

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29445371
DOI: 10.3389/fimmu.2018.00057

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of MicroRNA on Regulatory T Cells and Implications for Adoptive Cellular Therapy to Ameliorate Graft-versus-Host DiseasePMID 29445371Read ↗

Effects of Non-Coding RNA on Regulatory T Cells and Implications for Treatment of Immunological Diseases.Semantic proximity Read ↗

The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease.Semantic proximity Read ↗

Dissection of the microRNA transcriptomes of CD4 <sup>+</sup> T cell subsets in autoimmune inflammation identifies novel regulators of disease pathogenesisSemantic proximity Read ↗

Inhibition of microRNA-155 ameliorates experimental autoimmune myocarditis by modulating Th17/Treg immune responseSemantic proximity Read ↗

miRNAs Alter T Helper 17 Cell Fate in the Pathogenesis of Autoimmune DiseasesSemantic proximity Read ↗

Blockade of miR-142-3p promotes anti-apoptotic and suppressive function by inducing KDM6A-mediated H3K27me3 demethylation in induced regulatory T cellsSemantic proximity Read ↗

MicroRNAs in the regulation of Th17/Treg homeostasis and their potential role in uveitisSemantic proximity Read ↗

Re-evaluating Strategies to Define the Immunoregulatory Roles of miRNAs.Semantic proximity Read ↗

miR-23∼27∼24 clusters control effector T cell differentiation and function.Semantic proximity Read ↗

Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity.Semantic proximity Read ↗

Serum microRNA Profiles Serve as Novel Biomarkers for Autoimmune DiseasesSemantic proximity Read ↗

Comprehensive analysis of miRNA expression in T-cell subsets of rheumatoid arthritis patients reveals defined signatures of naive and memory TregsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.