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Collagen I and collagen III polymorphisms in women with pelvic organ prolapse.

Neurourology and urodynamics - 1 Sept 2020

Batista Nilce C, Bortolini Maria A T, Silva Rebecca S P, Teixeira Juliana B, Melo Natália C, Santos Renata G M, Pepicelli Fernanda A A, Castro Rodrigo A

Abstract excerpt

AIMS: Verify the presence of the single nucleotide polymorphisms rs1800012 of the collagen I (COL1A1) and rs1800255 of the collagen III (COL3A1) genes and their association with pelvic organ prolapse (POP) in Brazilian women and to determine risk factors for POP. METHODS: We assessed 826 postmenopausal women divided into POP (stages III and IV) and control groups (stages 0 and I) by examination and peripheral...

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PMID: 32692893
DOI: 10.1002/nau.24447

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