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Article

Genetic variants in three genes and smoking show strong associations with susceptibility to exudative age-related macular degeneration in a Chinese population.

Chinese medical journal - 20 Dec 2008

Chu Jie, Zhou Cheng-chao, Lu Ning, Zhang Xue, Dong Fang-tian

Abstract excerpt

BACKGROUND: The present study was undertaken to replicate the associations of representative polymorphisms in three genes (complement factor H (CFH), complement factor B (BF) and HtrA serine peptidase 1 (HTRA1)) with exudative age-related macular degeneration (AMD) in a Han Chinese population, and to test if the modifiable environmental factors affect AMD susceptibility associated with different type of genotype...

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Source

Identifiers

PMID: 19187590

Genes

CFH
HTRA1

Variants

rs1061170

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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