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[Establishment of the methods to detect nucleophosmin gene and its mutation in acute myelogenous leukemia].

Zhongguo shi yan xue ye xue za zhi - 1 Aug 2008

He Peng, Zhang Ling, Luo Zhan-Peng, Yang Song, Zhong Xiao-Ming, Cai Xiao-Zhong

Abstract excerpt

This study was aimed to establish the PCR methods to detect nucleophosmin (NPM) gene and its mutation. 2 leukemia cell lines and 23 specimens from patients with acute myelogenous leukemia (AML) were investigated. The level of NPM mRNA was detected by RT-PCR. The exon-12 of NPM gene in leukemia cell lines was amplified by PCR and sequenced. Using the plasmid containing cDNA of NPM mutation A as a positive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18718053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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