Article
[The Collaborative Cross, a groundbreaking tool to tackle complex traits].
Medecine sciences : M/S - 1 Jan 2012
Panthier Jean-Jacques, Montagutelli Xavier
Abstract excerpt
Complex traits, like the susceptibility to common diseases, are controlled by numerous genomic regions which individual effect is generally weak. These observations led geneticists to develop an experimental system to dissect the genetic of complex traits in the mouse. The Collaborative Cross (CC) is a genetic reference population of over 300 inbred lines derived from eight inbred strains of three Mus musculus...
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