Article
Sister chromatid cohesion role for CDC28-CDK in Saccharomyces cerevisiae.
Genetics - 1 Sept 2008
Brands Alex, Skibbens Robert V
Abstract excerpt
High-fidelity chromosome segregation requires that the sister chromatids produced during S phase also become paired during S phase. Ctf7p (Eco1p) is required to establish sister chromatid pairing specifically during DNA replication. However, Ctf7p also becomes active during G2/M in response to DNA damage. Ctf7p is a phosphoprotein and an in vitro target of Cdc28p cyclin-dependent kinase (CDK), suggesting one...
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