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Article

A phosphorylation-independent role for the yeast cyclin-dependent kinase activating kinase Cak1.

Gene - 15 Nov 2009

Kim Su-Hwa, Gadiparthi Keerthi, Kron Stephen J, Kitazono Ana A

Abstract excerpt

Cdc28 is the main cyclin-dependent kinase (CDK) directing the cell cycle in the budding yeast Saccharomyces cerevisiae. Besides cyclin binding, Cdc28 requires phosphorylation by the Cak1 kinase to achieve full activity. We have previously isolated carboxy-terminal cdc28(CST) mutants that are temp...

Topics

Binding Sites
CDC28 Protein Kinase, S cerevisiae
Cell Cycle
Cyclin-Dependent Kinases
Enzyme Stability
Gene Dosage
Genes, Fungal
Multiprotein Complexes
Mutation
Phosphorylation
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Two-Hybrid System Techniques

Cyclin-Dependent Kinase-Activating Kinase

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Identifiers

PMID: 19647054
DOI: 10.1016/j.gene.2009.07.016
PMCID: PMC4562314

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-19647054-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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A phosphorylation-independent role for the yeast cyclin-dependent kinase activating kinase Cak1.PMID 19647054Read ↗

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