Article
DNA metabolism gene CDC7 from yeast encodes a serine (threonine) protein kinase.
Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 1990
Hollingsworth R E, Sclafani R A
Abstract excerpt
The yeast Cdc7 protein is indispensable to initiation of nuclear DNA replication, based on the phenotype of the conditional, temperature-sensitive (ts) cdc7 mutants at the restrictive temperature. This protein has likewise been implicated in commitment to meiotic DNA recombination and induced mutagenesis, which may result from error-prone DNA repair. Our previous work revealed sequence similarity between the Cdc7...
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