Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Synaptic homeostasis in a zebrafish glial glycine transporter mutant.

Journal of neurophysiology - 1 Oct 2008

Mongeon Rebecca, Gleason Michelle R, Masino Mark A, Fetcho Joseph R, Mandel Gail, Brehm Paul, Dallman Julia E

Abstract excerpt

Truncated escape responses characteristic of the zebrafish shocked mutant result from a defective glial glycine transporter (GlyT1). In homozygous GlyT1 mutants, irrigating brain ventricles with glycine-free solution rescues normal swimming. Conversely, elevating brain glycine levels restores motility defects. These experiments are consistent with previous studies that demonstrate regulation of global glycine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Axons
Share to Electroshock
Share to Escape Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Excitatory Postsynaptic Potentials

Share to Motor Neurons

Share to Neuroglia

Share to Receptors, Glycine

Share to Synapses

Source

Open in PubMed Open full text

Identifiers

PMID: 18715895
DOI: 10.1152/jn.90596.2008
PMCID: PMC2576222

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Synaptic homeostasis in a zebrafish glial glycine transporter mutant.PMID 18715895Read ↗

The zebrafish shocked gene encodes a glycine transporter and is essential for the function of early neural circuits in the CNS.Semantic proximity Read ↗

Glial glycine transporter 1 function is essential for early postnatal survival but dispensable in adult mice.Semantic proximity Read ↗

Inactivation of the glycine transporter 1 gene discloses vital role of glial glycine uptake in glycinergic inhibition.Semantic proximity Read ↗

A critical role for glycine transporters in hyperexcitability disordersSemantic proximity Read ↗

Glycine receptor knock-in mice and hyperekplexia-like phenotypes: comparisons with the null mutant.Semantic proximity Read ↗

Gene knockout of glycine transporter 1: characterization of the behavioral phenotype.Semantic proximity Read ↗

GlyT1 determines the glycinergic phenotype of amacrine cells in the mouse retina.Semantic proximity Read ↗

Disruption of Eaat2b, a glutamate transporter, results in abnormal motor behaviors in developing zebrafish.Semantic proximity Read ↗

Disruption of glycine transporter 1 restricted to forebrain neurons is associated with a procognitive and antipsychotic phenotypic profile.Semantic proximity Read ↗

Deletion of the mouse glycine transporter 2 results in a hyperekplexia phenotype and postnatal lethality.Semantic proximity Read ↗

Characterization of the zebrafish gabra1sa43718/sa43718 germline loss of function allele confirms a function for Gabra1 in motility and nervous system development.Semantic proximity Read ↗

A zebrafish gephyrinb mutant distinguishes synaptic and enzymatic functions of Gephyrin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.