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Article

Characterization of the zebrafish gabra1sa43718/sa43718 germline loss of function allele confirms a function for Gabra1 in motility and nervous system development.

Differentiation; research in biological diversity - 1 Jan 2000

Reyes-Nava Nayeli G, Paz David, Pinales Briana E, Perez Isaiah, Gil Claudia B, Gonzales Annalise V, Grajeda Brian I, Estevao Igor L, Ellis Cameron C, Castro Victoria L, Quintana Anita M

Abstract excerpt

Mutation of the GABRA1 gene is associated with neurodevelopmental defects and epilepsy. GABRA1 encodes for the α1 subunit of the γ-aminobutyric acid type A receptor (GABAAR), which regulates the fast inhibitory impulses of the nervous system. Multiple model systems have been developed to understand the function of GABRA1, but these models have produced complex and, at times, incongruent data. Thus, additional...

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PMID: 38908344
DOI: 10.1016/j.diff.2024.100790

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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