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Article

Disruption of Eaat2b, a glutamate transporter, results in abnormal motor behaviors in developing zebrafish.

Developmental biology - 15 Feb 2012

McKeown Kelly Anne, Moreno Rosa, Hall Victoria L, Ribera Angeles B, Downes Gerald B

Abstract excerpt

Analysis of zebrafish mutants that have defects in motor behavior can allow entrée into the hindbrain and spinal cord networks that control locomotion. Here, we report that zebrafish techno trousers (tnt) locomotor mutants harbor a mutation in slc1a2b, which encodes Eaat2b, a plasma membrane glutamate transporter. We used tnt mutants to explore the effects of impaired glutamate transporter activity on locomotor...

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Identifiers

PMID: 22094018
DOI: 10.1016/j.ydbio.2011.11.001
PMCID: PMC4013685

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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