Gamma frailty model for linkage analysis with application to interval-censored migraine data.

Abstract excerpt

For many diseases, it seems that the age at onset is genetically influenced. Therefore, the age-at-onset data are often collected in order to map the disease gene(s). The ages are often (right) censored or truncated, and therefore, many standard techniques for linkage analysis cannot be used. In this paper, we present a correlated frailty model for censored survival data of siblings. The model is used for testing...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Clinical Protocols
• Share to Likelihood Functions