Article
Antiretroviral genotypic resistance in plasma RNA and whole blood DNA in HIV-1 infected patients failing HAART.
Journal of medical virology - 1 Oct 2008
Saracino Annalisa, Gianotti Nicola, Marangi Marianna, Cibelli Donatella C, Galli Andrea, Punzi Grazia, Monno Laura, Lazzarin Adriano, Angarano Gioacchino
Abstract excerpt
The extent to which HIV-1 proviral DNA mutations cause clinically relevant antiretroviral resistance is still controversial. Paired plasma HIV-1 RNA and whole blood DNA were compared in patients failing HAART to investigate if the additional knowledge of archived mutations could improve the selec...
Topics
- Anti-HIV Agents
- Antiretroviral Therapy, Highly Active
- DNA Mutational Analysis
- DNA, Viral
- Drug Resistance, Viral
- HIV Infections
- HIV Protease
- HIV Reverse Transcriptase
- HIV-1
- Humans
- Molecular Sequence Data
- Multicenter Studies as Topic
- Mutation