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Article

Mitochondrial localization of DJ-1 leads to enhanced neuroprotection.

Journal of neuroscience research - 1 Jan 2009

Junn Eunsung, Jang Won Hee, Zhao Xin, Jeong Byeong Seon, Mouradian M Maral

Abstract excerpt

Mutations in DJ-1 (PARK7) cause recessively inherited Parkinson's disease. DJ-1 is a multifunctional protein with antioxidant and transcription modulatory activity. Its localization in cytoplasm, mitochondria, and nucleus is recognized, but the relevance of this subcellular compartmentalization to its cytoprotective activity is not fully understood. Here we report that under basal conditions DJ-1 is present...

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Source

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Identifiers

PMID: 18711745
DOI: 10.1002/jnr.21831
PMCID: PMC2752655

Genes

PARK7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mitochondrial localization of DJ-1 leads to enhanced neuroprotection.PMID 18711745Read ↗

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